Cell Therapy

Stem Cell Transplants Extend Life for Multiple Myeloma Patients

Researchers at UC Davis have confirmed that autologous hematopoietic stem cell transplant improves survival for people suffering from multiple myeloma, yet many potentially eligible patients never undergo the procedure. Using data from two extensive California databases, the team showed median overall survival for transplant patients was around 73 months, while controls who did not receive the procedure lived around 50 months. The study was published June 11 in the Journal
cancer Cell Therapy

Blood Cancer Treatment May Age Immune Cells As Much As 30 Years

Certain cancer treatments are known to take a toll on patients, causing side effects like fatigue, nausea and hair loss. Now, scientists are investigating whether some treatments can cause another long-term side effect: premature aging of important disease-fighting cells. University of North Carolina Lineberger Comprehensive Cancer Center researchers, by tracking a molecular marker that has been shown to increase in white blood cells as people age, have uncovered clues that
cancer Cell Therapy Pharmaceuticals Prescriptions

Antibody-Based Drug Helps “Bridge” Leukemia Patients to Curative Treatment

In a randomized Phase III study of the drug inotuzumab ozogamicin, a statistically significant percentage of patients with acute lymphoblastic leukemia (ALL) whose disease had relapsed following standard therapies, qualified for stem cell transplants. Inotuzumab ozogamicin, also known as CMC-544, links an antibody that targets CD22, a protein found on the surface of more than 90 percent of ALL cells. Once the drug connects to CD22, the ALL cell draws
Biotechnology Cell Therapy

First Skin-to-Eye Stem Cell Transplant in Humans Successful

Researchers have safely transplanted stem cells derived from a patient’s skin to the back of the eye in an effort to restore vision. The research is being presented at the 2016 Annual Meeting of the Association for Research in Vision and Ophthalmology (ARVO) this week in Seattle, Wash. A small piece of skin from the patient’s arm was collected and modified into induced pluripotent stem cells (iPSC). The iPSCs were