Biotechnology

New approach could jumpstart breathing after spinal cord injury

 A research team at the Krembil Research Institute in Toronto has developed an innovative strategy that could help to restore breathing following traumatic spinal cord injury. The team, led by principal investigator Dr. Michael Fehlings – a neurosurgeon/neuroscientist, specialist in spinal cord injury and senior scientist at UHN – published its findings today in the […]

Biotechnology

Researchers find adult stem cell characteristics in aggressive cancers from different tissues

UCLA researchers have discovered genetic similarities between the adult stem cells responsible for maintaining and repairing epithelial tissues — which line all of the organs and cavities inside the body — and the cells that drive aggressive epithelial cancers. Their findings could bring about a better understanding of how aggressive, treatment-resistant cancers develop and progress, and […]

Biotechnology

First Mouse Model to Mimic Lung Disease Could Speed Discovery of More Effective Treatments

Penn Study Details Model of Pulmonary Fibrosis, Which Kills More Than 40,000 Each Year The biggest hurdle to finding effective therapies for idiopathic pulmonary fibrosis (IPF) – a life-threatening condition in which the lungs become scarred and breathing is increasingly difficult – has been the inability to fully model the disease in animals, limiting the […]

cancer Cancer Discovery

Foundation for the National Institutes of Health and Cancer Research Institute Announce New Collaboration in Cancer Immunotherapy

The Foundation for the National Institutes of Health (FNIH) and the Cancer Research Institute (CRI) announced today that FNIH has selected CRI to be its source of landscape intelligence in immuno-oncology, also called cancer immunotherapy. This collaboration draws on CRI’s 65 years of leadership in cancer immunotherapy and its first-in-class immunotherapy landscape analyses produced by […]

cancer Cancer Discovery

By Forming Clots in Tumors, Immune Cell AIDS Lung Cancer’s Spread

University of North Carolina Lineberger Comprehensive Cancer Center researchers have found that helping to to form clots within tumors, immune cells that flock to a particular type of lung cancer are actually building a foundation for the tumor to spread within the body. In the journal Nature Communications, researchers report for a particular subset of […]

Uncategorized

New Clues to COPD Linked to Proteostasis Imbalance Caused by Cigarette Smoke

Few threats to public health are as perilous as cigarette smoking, with more than 435,000 Americans dying each year of tobacco-related pulmonary illnesses such as chronic obstructive pulmonary disease (COPD). COPD ranks as the third-leading cause of tobacco-related morbidity and mortality worldwide in 2012 and the global cost of illness related to COPD is expected […]

Uncategorized

Belfast Scientists Develop New Treatment to Prolong Life of Those with Cystic Fibrosis

Scientists at Queen’s University Belfast have discovered a new molecule which has the potential to prolong the life of individuals with cystic fibrosis (CF).   The molecule represents a possible future treatment and works by altering cellular ion channels resulting in improved airway hydration and significantly increased mucus clearance. For individuals with CF, normal airway clearance […]

Laboratory Technology

Penn and Rutgers Researchers Discover New Pathway That May Trigger Asthma

Asthma is an enormous public health problem that continues to grow larger, in part because scientists don’t fully understand how it is caused. Existing therapies don’t cure the disease and often don’t even significantly alleviate the symptoms. Now, scientists from the Perelman School of Medicine at the University of Pennsylvania and Rutgers University have identified […]