Biotechnology Clinical Trials Pharmaceuticals

A Change in Bacteria’s Genetic Code Holds Promise of Longer-Lasting Drugs

By altering the genetic code in bacteria, researchers at The University of Texas at Austin have demonstrated a method to make therapeutic proteins more stable, an advance that would improve the drugs’ effectiveness and convenience, leading to smaller and less frequent doses of medicine, lower health care costs and fewer side effects for patients with […]

Biotechnology cancer

Drugs, Diseases and Proteins: New Archive Helps Precision Medicine, Drug Development

UNM Cancer Center Scientist co-leads international drug targets effort to create open-source archive for drug discovery, development, and safety Most aspirin users don’t know what aspirin does to make you feel better. Most doctors and scientists didn’t know, either, until recently. In fact, scientists know how only a handful of drugs really work and they […]

Biotechnology cancer

Structure of Atypical Cancer Protein Paves Way for Drug Development

Blocking newly discovered binding sites may fight tumor spread A team of researchers from Case Western Reserve University School of Medicine has helped uncover the elusive structure of a cancer cell receptor protein that can be leveraged to fight disease progression. Previous studies have showed blocking the receptor can slow tumor growth and metastasis in […]

cancer Hepatitis Vaccines

Scientists Uncover Why Hepatitis C Virus Vaccine Has Been Difficult To Make

Researchers have been trying for decades to develop a vaccine against the globally endemic hepatitis C virus (HCV). Now scientists at The Scripps Research Institute (TSRI) have discovered one reason why success has so far been elusive. Using a sophisticated array of techniques for mapping tiny molecular structures, the TSRI scientists analyzed a lab-made version of […]

cancer Cancer Discovery

Researchers Restore Drug Sensitivity in Breast Cancer Tumors

A team of Case Western Reserve University School of Medicine cancer researchers has uncovered one way certain tumors resist vital medication. In the study published in Oncotarget, the researchers studied tumor biopsies collected from breast cancer patients before and after treatment with the go-to breast cancer drug trastuzumab (also known as Herceptin). Some of the […]