Biotechnology cancer Cancer Discovery

New Approach May Curb Treatment-Related Skin Fibrosis in Cancer Patients

A clinical-scientific team specializing in head-and-neck cancer has identified a way to manipulate metabolism to potentially curb skin fibrosis -- a common side effect of radiotherapy affecting quality of life of cancer survivors. The study findings from the laboratory of principal investigator Dr. Fei-Fei Liu, Chief, Radiation Oncology, Princess Margaret Cancer Centre, University Health Network, are published online today in Nature Metabolism (DOI:10.1038/s42255-018-0008-5). Dr. Liu is also Professor and Chair,
cancer Clinical Trials

Prostate Cancer Clinical Trial Shows Treating with Precision Radiotherapy Reduces Course of Treatment by 50%

An Ontario-led international clinical trial with 1,206 men with localized prostate cancer shows that compressing radiation treatments into four weeks from eight delivers similar outcomes. The findings, published online today in the Journal of Clinical Oncology, provide a new standard of care worldwide, which the participating centres have already adopted, says co-principal investigator Charles Catton, radiation oncologist, Princess Margaret Cancer Centre, University Health Network. Dr. Catton is also a Professor,
Biotechnology rare diseases

Stem Cell-Based Test Predicts Leukemia Patients’ Response to Therapy to Help Tailor Treatment

Newswise — (TORONTO, Canada – Dec. 7, 2016) – Leukemia researchers at Princess Margaret Cancer Centre have developed a 17-gene signature derived from leukemia stem cells that can predict at diagnosis if patients with acute myeloid leukemia (AML) will respond to standard treatment. The findings, published online today in Nature, could potentially transform patient care in AML by giving clinicians a risk scoring tool that within a day or two