cancer Cancer Discovery

Obesity is Shifting Cancer to Young Adults

A Case Western Reserve University School of Medicine researcher has compiled evidence from more than 100 publications to show how obesity increases risk of 13 different cancers in young adults. The meta-analysis describes how obesity has shifted certain cancers to younger age groups, and intensified cellular mechanisms promoting the diseases. Cancer typically associated with older […]

Biotechnology cancer Cell Therapy Clinical Trials Heart Health

Bariatric surgery lowers cancer risk for severely obese patients

Severely obese patients who undergo bariatric surgery lower their risk of developing cancer by at least a third, according to a University of Cincinnati (UC) College of Medicine researcher leading a large retrospective cohort study of patients in the western United States. “We found having bariatric surgery is associated with a reduced risk of cancer, […]

Biotechnology Prodrug

Scientists Discover Common Obesity and Diabetes Drug Reduces Rise in Brain Pressure

Research led by the University of Birmingham, published today in Science Translational Medicine, has discovered that a drug commonly used to treat patients with either obesity or Type II diabetes could be used as a novel new way to lower brain pressure. Raised brain pressure is common in emergency situations such as traumatic brain injury, […]

Biotechnology Clinical Trials Pharmaceuticals

New combination of anti-obesity drugs may have beneficial effects

Research conducted in the Perelman School of Medicine at the University of Pennsylvania has revealed that a unique combination of hormone-based drugs can produce enhanced weight loss in laboratory tests with obese animals. The research is to be presented this week at the Annual Meeting of the Society for the Study of Ingestive Behavior (SSIB), […]

Biotechnology

Obesity risk factors dropped in preschoolers in prevention program

Preschoolers from low-income families living in cities that took part in a two-year community-wide intervention to foster healthy eating and lifestyle habits consumed fewer sugary drinks, got more sleep, and showed improvement in weight, according to a study led by a researcher at NewYork-Presbyterian/Columbia University Medical Center (CUMC). The study–one of a trio of studies […]

Biotechnology Diabetes

Study reveals sweetened drinks during pregnancy puts infants at higher risk for obesity

A recent Danish study of children born to women with gestational diabetes, found that maternal daily consumption of artificially-sweetened beverages during pregnancy was associated with a higher body mass index score and increased risk of overweight/obesity at 7 years. Artificial sweeteners are widely replacing caloric sweeteners, due to the health concern related to sugar-sweetened beverages […]

Biotechnology

Childhood obesity causes lasting damage to the body

Obesity in childhood has long term health implications stretching into adulthood, a new study in the journal Obesity Reviews reveals. Examining data collected from over 300,000 participants across 18 studies, researchers from the University of Surrey identified increased arterial damage and enhanced likelihood of pre diabetes in participants who were obese in childhood. The damage, […]

Biotechnology

Children with Asthma May Be at Higher Obesity Risk

Children with asthma may be more likely to become obese later in childhood or in adolescence, according to new research published online ahead of print in the American Thoracic Society’s American Journal of Respiratory and Critical Care Medicine. In “Effects of Childhood Asthma on the Development of Obesity among School-Aged Children,” researchers report that young […]

Biotechnology Cell Therapy

Rare Obesity Syndrome Therapeutic Target Identified

Columbia University Medical Center (CUMC) researchers have discovered that a deficiency of the enzyme prohormone covertase (PC1) in the brain is linked to most of the neuro-hormonal abnormalities in Prader-Willi syndrome, a genetic condition that causes extreme hunger and severe obesity beginning in childhood. The discovery provides insight into the molecular mechanisms underlying the syndrome […]

cancer Cancer Discovery

The Complex Crosstalk Between Obesity and Breast Cancer

A new study published in the Journal of Cell Physiology describes how inflammation that characterizes fatty tissue is one of the main microenvironment actors responsible for promoting cancer. The authors also describe the involvement of steroid hormones and others factors produced by adipose tissue in breast cancer development. The study, “Multifaceted breast cancer: the molecular […]