Biotechnology

Mitochondrial Protein in Cardiac Muscle Cells Linked to Heart Failure, Study Finds

Reducing a protein found in the mitochondria of cardiac muscle cells initiates cardiac dysfunction and heart failure, a finding that could provide insight for new treatments for cardiovascular diseases, a study led by Georgia State University has shown. The researchers discovered that reducing an outer mitochondrial membrane protein, FUN14 domain containing 1 (FUNDC1), in cardiac […]

Neurodegenerative diseases Neurology

Study Discovers Potential New Target For Treatment Of Spinal Muscular Atrophy

For the first time, scientists found that in spinal muscular atrophy (SMA), the affected nerve cells that control muscle movement, or motor neurons, have defects in their mitochondria, which generate energy used by the cell. Impaired mitochondrial function and structure in motor neurons were discovered before symptoms occurred, suggesting a role in disease development. These […]

Genomes

Get a clue: Biochemist studies fruit fly to understand Parkinson’s disease, muscle wasting

The fruit fly may help us be less clueless about human muscle development and Parkinson’s disease. Erika Geisbrecht, Kansas State University associate professor of biochemistry and molecular biophysics, is studying the fruit fly, or Drosophila melanogaster, to understand a gene called clueless, or clu. Geisbrecht and her research team have found a connection between clu […]