Medical Devices

Gut check: Swallowed capsule could spot trouble, send alert

(AP) Scientists have developed a swallowed capsule packed with tiny electronics and millions of genetically engineered living cells that might someday be used to spot health problems from inside the gut. The capsule was tested in pigs and correctly detected signs of bleeding, researchers at the Massachusetts Institute of Technology reported Thursday in the journal Science . At more than an inch long, it will have to be made smaller
Infectious Diseases

UCI-Harvard research may help combat the deadly gastrointestinal infection C. diff

Researchers from the University of California, Irvine and Harvard University have discovered how the Clostridium difficile toxin B (TcdB) recognizes the human Frizzled protein, the receptor it uses to invade intestinal cells and lead to deadly gastrointestinal infections. The findings, published today in Science, could pave the way for new C. diff antitoxins and also show potential for the development of novel anti-cancer drugs. In a C. diff infection (CDI),