Cancer Discovery

Eureka Therapeutics Achieves Regression of Metastatic Liver Cancer Using T-Cell Therapy

Eureka Therapeutics, a clinical stage biopharmaceutical company with the goal of curing cancer by developing novel T-cell therapies that harness the evolutionary power of the immune system, announced preliminary safety and clinical results from its ongoing proof-of-concept study of ET140202 T-cell therapy in AFP-positive patients with hepatocellular carcinoma (HCC), the most prevalent form of liver […]

Cancer Discovery

Scientists build a new model of CAR-T cells — Ones with Powerful “Armor” that allow them to fight Solid Tumors

Engineered T-cell therapy, and in particular CAR T-cells, have shown efficacy in CD-19+ blood cancer such as lymphomas and leukemias. However, to date, T-cell therapies have found little success in solid tumors – in part due to the immunosuppressive tumor microenvironment. Checkpoint inhibitors, on the other hand, have been proven effective at empowering the immune […]