Biotechnology Clinical Trials Pharmaceuticals rare diseases

New Insight Into Huntington’s Disease May Open Door to Drug Development

McMaster University researchers have developed a new theory on Huntington’s disease which is being welcomed for showing promise to open new avenues of drug development for the condition. Huntington’s disease is caused by a mutation in the gene that makes the protein called huntingtin. A team of researchers led by McMaster has found there is […]

Biotechnology cancer rare diseases

Study Reports Possible Novel Method for Stopping Untreatable Pediatric Brain Cancer

Researchers used an experimental molecular therapy in preclinical laboratory tests to effectively treat several types of deadly pediatric brain cancer and now propose advancing the treatment to clinical testing in children. Scientists at the Cincinnati Children’s Cancer and Blood Diseases Institute report in the journal Molecular Cancer Therapeutics testing the small molecule 6-thio-2’deoxyguanosine (6-thio-dG) in […]

Biotechnology cancer Cancer Discovery Genomes

Spotting Dna Repair Genes Gone Awry

Researchers led by Ludwig Cancer Research scientist Richard Kolodner have developed a new technique for sussing out the genes responsible for helping repair DNA damage that, if left unchecked, can lead to certain cancers. Genome instability suppressing (GIS) genes play an important role in correcting DNA damage involving the improper copying or reshuffling of large […]