cancer Cancer Discovery

Queen’s Researchers Discover Ground-Breaking Process Which Destroys Bowel Cancer Cells

Researchers at Queen’s University Belfast have discovered a ground-breaking therapeutic process that can target and kill bowel cancer cells, which may improve survival rates for bowel cancer patients globally. The research, which has been published in the prestigious journal of Molecular Cancer Therapeutics, is deemed the first of its kind with the discovery of a novel treatment […]

cancer Cancer Discovery

Removing the Most Common p53 Mutation in Colorectal Cancer Halts Disease Progression

A Stony Brook pathologist and colleagues publish findings in Cancer Cell By genetically manipulating and removing the most common mutant form of the p53 gene that promotes colorectal cancer in humans, an international team of scientists demonstrated that this therapy reduces tumor growth and tissue invasion. Led by Ute Moll, MD, Professor and cancer biologist in […]

Infectious Diseases

Immune Cells That Create and Sustain Chronic Inflammatory Bowel Disease Identified

These immune cells could become therapeutic targets to treat Crohn’s disease and ulcerative colitis. In preclinical experiments, Laurie Harrington, Ph.D., and colleagues at the University of Alabama at Birmingham have discovered a subset of immune cells that create and sustain chronic inflammatory bowel disease. These cells could become potential therapeutic targets to ameliorate or cure Crohn’s disease […]

cancer Cancer Discovery

Simultaneous Chemotherapy and Immunotherapy May Be Better for Some Metastatic Bladder Cancer Patients

Researchers from Mount Sinai and Sema4, a health information company and Mount Sinai venture, have discovered that giving metastatic bladder cancer patients simultaneous chemotherapy and immunotherapy is safe and that patients whose tumors have certain genetic mutations may respond particularly well to this combination approach, according to the results of a clinical trial published in European […]

Alzheimers and Dementia

Researchers Identify Epigenetic Orchestrator of Pancreatic Cancer Cells

Genentech researchers have identified an enzyme that shifts pancreatic cancer cells to a more aggressive, drug-resistant state by epigenetically modifying the cells’ chromatin. The study, which will be published December 11 in the Journal of Cell Biology, suggests that targeting this enzyme could make pancreatic cancer cells more vulnerable to existing therapies that currently have only […]

Biotechnology

Immune Cells Produce Wound Healing Factor, Could Lead To New IBD Treatment

Specific immune cells have the ability to produce a healing factor that can promote wound repair in the intestine, a finding that could lead to new, potential therapeutic treatments for inflammatory bowel disease (IBD), according to a new research study. The research team, led by Georgia State University and the University of Michigan, wanted to […]

Biotechnology cancer Cancer Discovery

Precision Prevention of Colorectal Cancer

Precision medicine’s public face is that of disease — and better treatments for that disease through targeted therapies. But precision medicine has an unsung partner that could affect the lives of many more people: Precision prevention — a reflection of the growing realization that preventing cancer and other diseases may not be one-size-fits-all. “Precision medicine […]