Biotechnology Diabetes Immunotherapies

Untimely Immune Cell Clocks May Contribute To Obesity And Diabetes In Shift Workers

About 15 million Americans don’t have a typical nine-to-five workday, and many of these—nurses, firefighters and flight attendants, among many other professions—may see their schedule change drastically one week to the next. As a result, these shift workers’ biological clocks, which keep track of the time of day, cannot keep accurate time, potentially making the negative […]

Diabetes

Kidney Disease Increases Risk of Diabetes, Study Shows Elevated urea levels likely a culprit

Diabetes is known to increase a person’s risk of kidney disease. Now, a new study from Washington University School of Medicine in St. Louis suggests that the converse also is true: Kidney dysfunction increases the risk of diabetes. Further, the researchers deduced that a likely culprit of the two-way relationship between kidney disease and diabetes […]

Biotechnology Clinical Trials Gene Therapy rare diseases

Scientists make a major breakthrough to treat fibrotic diseases that cause organ failure

Researchers from Duke-NUS Medical School (Duke-NUS) and the National Heart Centre Singapore (NHCS) have discovered that a critical protein, known as interleukin 11 (IL11) is responsible for fibrosis and causes organ damage. While it is surprising that the importance of IL11 has been overlooked and misunderstood for so long, it has now been very clearly […]

Biomarkers

Biomarkers Pinpoint the Effects of Thirdhand Smoke on Liver and Lung Found to Worsen Over Time

Researchers at the University of California, Riverside have found that thirdhand-smoke (THS) exposure has a significant effect on health as early as one month after initiation of exposure – an effect that worsens with time. THS results when exhaled smoke and smoke emanating from the tip of burning cigarettes gets on surfaces such as clothing, […]

Biotechnology Prodrug

Scientists Discover Common Obesity and Diabetes Drug Reduces Rise in Brain Pressure

Research led by the University of Birmingham, published today in Science Translational Medicine, has discovered that a drug commonly used to treat patients with either obesity or Type II diabetes could be used as a novel new way to lower brain pressure. Raised brain pressure is common in emergency situations such as traumatic brain injury, […]

Diabetes

Towards a safe and scalable cell therapy for type 1 diabetes by simplifying beta cell differentiation

More than 36 million people globally are affected by type 1 diabetes (T1D), a lifelong disorder where insulin producing cells are attacked and destroyed by the immune system resulting in deficient insulin production that requires daily blood glucose monitoring and administration of insulin. While successful outcomes from islet transplantations have been reported, very few patients […]

Biotechnology Diabetes

Higher BMI linked with increased risk of high blood pressure, heart disease, type 2 diabetes

Results of a new study add to the evidence of an association between higher body mass index (BMI) and increased risk of cardiometabolic diseases such as hypertension, coronary heart disease, type 2 diabetes, according to a study published by JAMA Cardiology. A connection between higher BMI and cardiometabolic disease risk usually arise from observational studies […]

Diabetes

Improved Options for Diabetics: Insurance Coverage Now Available for Dario’s New Glucose Monitoring Device and App

More than 387 million people are living with diabetes worldwide. This number is expected to grow to 592 million by 2035. Effective daily blood glucose monitoring is a huge factor in the health and wellbeing of diabetics. A new mobile health app and all-in-one blood glucose monitor system from DarioHealth Corp. (DRIO) can improve monitoring […]

Diabetes

Study Suggests New Way to Prevent Vision Loss in Diabetics and Premature Babies

Researchers at Bascom Palmer Eye Institute, part of the University of Miami Miller School of Medicine, have identified a new molecule that induces the formation of abnormal blood vessels in the eyes of diabetic mice. The study, “Secretogranin III as a disease-associated ligand for antiangiogenic therapy of diabetic retinopathy,” which will be published March 22 […]

Diabetes

Scientists Find Therapeutic Target for Diabetes-Related Blindness

Study reveals single cell type and surface molecule sufficient to cause common complication Specific cells in the retina trigger inflammation and vision impairment associated with diabetes, according to new research out of Case Western Reserve University School of Medicine. The findings unexpectedly implicate Müller cells—which provide structural support in the retina—as key drivers of the […]