Cancer Discovery

Scientists build a new model of CAR-T cells — Ones with Powerful “Armor” that allow them to fight Solid Tumors

Engineered T-cell therapy, and in particular CAR T-cells, have shown efficacy in CD-19+ blood cancer such as lymphomas and leukemias. However, to date, T-cell therapies have found little success in solid tumors – in part due to the immunosuppressive tumor microenvironment. Checkpoint inhibitors, on the other hand, have been proven effective at empowering the immune […]

Immunotherapies

Peer Reviewed Paper: Novel Immunotherapy Actives CD4 Helper T Cells using HLA-Class II Molecules

The findings detailed in an upcoming peer-reviewed paper provide a rationale for the encouraging clinical results observed with Bria-IMT™, an immunotherapy from BriaCell Therapeutics, in current and past clinical testing.  The paper will appear in Frontiers in Immunology, the 5th most cited journal in Immunology worldwide.  Bria-IMT™, also known as SV-BR-1-GM, has caused remarkable reduction […]