Cancer Discovery

Stunting cell ‘antennae’ could make cancer drugs work again

Scientists have uncovered a completely new way to make cancers sensitive to treatment - by targeting antenna-like structures on cells. Their study found that drug-resistant cancer cells have more and longer antennae than those which are killed by treatment. Blocking the growth of antennae reactivated a range of cancer treatments that had stopped working, the team at The Institute of Cancer Research, London, found. The researchers identified changes in cellular
Biotechnology Cell Therapy Regenerative Medice

Tissue Engineered Human Pancreas Cells Successfully Treat Diabetic Mice

Self-Condensation Process for Cells Generates Vascularized Organ Tissues for Transplant Researchers tissue-engineered human pancreatic islets in a laboratory that develop a circulatory system, secrete hormones like insulin and successfully treat sudden-onset type 1 diabetes in transplanted mice. In a study published by Cell Reports, the scientists use a new bioengineering process they developed called a self-condensation cell culture. The technology helps nudge medical science closer to one day growing human
Ophthalmology

NIH Discovery Brings Stem Cell Therapy for Eye Disease Closer to the Clinic

Scientists at the National Eye Institute (NEI), part of the National Institutes of Health, report that tiny tube-like protrusions called primary cilia on cells of the retinal pigment epithelium (RPE)—a layer of cells in the back of the eye—are essential for the survival of the retina’s light-sensing photoreceptors. The discovery has advanced efforts to make stem cell-derived RPE for transplantation into patients with geographic atrophy, otherwise known as dry age-related