Cancer Discovery

New Paper Highlights Role of Immune Stimulating Cells that Shrink Advanced Breast Cancer Tumors

The research team at BriaCell Therapeutics Corp., an immuno-oncology focused biotechnology company with a proprietary targeted immunotherapy technology, published a paper that sheds light on the potentially unique mechanism of action of BriaCell’s lead product candidate, Bria-IMT™, in the journal of Frontiers in Immunology, the 5th most cited journal in Immunology. The paper titled, SV-BR-1-GM, a Clinically Effective GM-CSF-Secreting Breast Cancer Cell Line, Expresses an Immune Signature and Directly Activates
Biotechnology Immunotherapies

Nuclear Pore Functions Are Essential for T Cell Survival

Study reveals an unexpected regulatory role for Nup210 in T cell homeostasis Nuclear pore complexes in the nuclear membrane not only control the transport of molecules into and out of the nucleus—they play an essential role in the survival of T cells. A new study by Sanford Burnham Prebys Medical Discovery Institute (SBP) researchers describes how a specific nuclear pore component is critical for the survival of circulating T cells.