cancer Cancer Discovery

A Cascade of Immune Processes Offers Insights to Triple-Negative Breast Cancer

Cancer is crafty. To survive and thrive, tumors find a way of thwarting our body’s natural systems. By looking at these systems, researchers at the University of Michigan Rogel Cancer Center have discovered that tumor cells reprogram metabolic pathways to gain control over a type of immune cell that allows cancer growth. Myeloid-derived suppressor cells live in the tumor microenvironment and work to block cancer immunity. They also encourage a stem cell-like
Immunotherapies

Peer Reviewed Paper: Novel Immunotherapy Actives CD4 Helper T Cells using HLA-Class II Molecules

The findings detailed in an upcoming peer-reviewed paper provide a rationale for the encouraging clinical results observed with Bria-IMT™, an immunotherapy from BriaCell Therapeutics, in current and past clinical testing.  The paper will appear in Frontiers in Immunology, the 5th most cited journal in Immunology worldwide.  Bria-IMT™, also known as SV-BR-1-GM, has caused remarkable reduction of tumor size in some patients with advanced metastatic breast cancer. Understanding Bria‑IMT™’s mechanism of