Cancer Cells Archives – The Bio Connection

Cancer Cells Thrive in Stiff Tissue, According to New Study

May 7, 2018 TheBioConnection Comment(0)

Stiffer breast tissue creates an environment more prone to cancer by enabling the disease to interfere with the surrounding healthy cells, according to a recent study published in Biomaterials. Scientists studying tumor growth and metastasis at the University of Notre Dame fabricated a human tissue model to examine how cancer cells interact with connective tissue […]

Biotechnology cancer Cancer Discovery

First Computer Program Developed to Detect DNA Mutations in Single Cancer Cells

April 26, 2016April 27, 2016 TheBioConnection Comment(0)

Researchers at The University of Texas MD Anderson Cancer Center have announced a new method for detecting DNA mutations in a single cancer cell versus current technology that analyzes millions of cells which they believe could have important applications for cancer diagnosis and treatment. The results are published in the April 18 online issue of […]

Genome sequencing found feasible and informative for pediatric cancer treatment October 18, 2018
Comprehensive genetic testing of tumors and non-cancerous tissue from pediatric cancer patients is a feasible and clinically useful approach that can guide patient care, according to new findings.
A 150-year-old drug might improve radiation therapy for cancer October 17, 2018
A drug first identified 150 years ago and used as a smooth-muscle relaxant might make tumors more sensitive to radiation therapy. Researchers found that the drug papaverine inhibits the respiration of mitochondria, the oxygen-consuming and energy-making components of cells, and sensitizes model tumors to radiation. They found that the drug does not affect the radiation […]
Vast leukemia dataset could help researchers match therapies to patients October 17, 2018
Data on the molecular makeup and drug sensitivity of hundreds of patient samples could accelerate progress against the aggressive blood cancer acute myeloid leukemia.
Combining genetic and sun exposure data improves skin cancer risk estimates October 17, 2018
By combining data on individuals' lifetime sun exposure and their genetics, researchers can generate improved predictions of their risk of skin cancer.
Breastfeeding protects infants from antibiotic-resistant bacteria October 17, 2018
A new study shows that infants that are breastfed for at least six months have less antibiotic-resistant bacteria in their gut compared with babies breastfed for a shorter time. On the other hand, antibiotic use by mothers increases the number of antibiotic-resistant bacteria in infants.
Lymphatic system, key player in human health October 16, 2018
Defects in the lymphatic system have been linked to a wide range of health consequences, but new findings of how the system works could lead to future therapies.
Age-related increase in estrogen may cause common men's hernia October 16, 2018
An age-related increase in estrogen may be the culprit behind inguinal hernias, a condition common among elderly men that often requires corrective surgery. Men could be treated with hormone inhibitor to strengthen muscle, the researcher suggests.
This RNA-based technique could make gene therapy more effective October 16, 2018
Biological engineers have devised a way to regulate the expression of messenger RNA once it gets into cells, giving them more precise control over gene therapy treatments for cancer and other diseases.
A bad influence: Interplay between tumor cells and immune cells October 16, 2018
Research has yielded new insights into the environment surrounding different types of lung tumors, and described how these complex cell ecosystems may in turn ultimately affect response to treatment.
Automated system identifies dense tissue, a risk factor for breast cancer, in mammograms October 16, 2018
Researchers have developed an automated model that assesses dense breast tissue in mammograms -- which is an independent risk factor for breast cancer -- as reliably as expert radiologists. This marks the first time a deep-learning model of its kind has successfully been used in a clinic on real patients, according to the researchers. With […]

Barclays has little confidence in the Mediclinic recovery story October 18, 2018
“We were disappointed by Mediclinic's first-half trading statement yesterday, which left us less confident in the recovery story”
ReNeuron’s CTX stem cell platform could be used to fight cancer October 18, 2018
ReNeuron thinks CTX could be reprogrammed and used to produce new non-donor-specific cell lines, including NK and T-Cells – the cells that can be modified to attack cancer cells
Regeneus receives intention notice for Progenza patent in Europe October 18, 2018
Last month, Edison increased their valuation for Regeneus to 87 cents per share.
Veravas looks to launch diagnostic products in April 2019 October 17, 2018
Veravas CEO John Forrest sits down with Proactive Investors' Christine Corrado at the BIO Investor Forum in San Francisco. Veravas is a privately held diagnostic company, its technology called VERAprep uses science-based innovation to rapidly commercialize high medical value products that detect low abundance biomarkers, facilitate the development of low-cost multiplexing tests, and reduce the effects […]
Dr. Reddy's expects to file BLA on its anti-cancer T-cell lymphoma drug end of 2019 October 17, 2018
Dr. Reddy’s Laboratories Ltd (NYSE:RDY) Senior Vice President Anil Namboodiripad spoke with Proactive Investors’ Christine Corrado at the Bio Investor Forum in San Francisco. The drug manufacturer’s areas of focus are gastrointestinal, cardiovascular, diabetology, oncology, pain management and dermatology.
Heidelberg Pharma looks to file IND Q2 2019 for its drug to treat cancer tumors October 17, 2018
Heidelberg Pharma AG (ETR:WL6) CEO Jan Schmidt-Brand spoke with Christine Corrado at the Bio Investor Forum in San Francisco. Heidelberg Pharma is a drug development company, which provides pre-clinical drug discovery and development services for the development of anti-cancer and anti-inflammatory drugs to pharmaceutical and biotechnology industries.
Mezzion Pharma expects topline data end of Q1 2019 October 17, 2018
Erik Emerson from Mezzion Pharma Co Ltd (KOSDAQ:140410) sat down with Proactive Investors' Christine Corrado at the Bio Investor Forum in San Francisco. The South Korean company is developing its drug Udenafil to treat single ventricle heart disease.
Aurora Cannabis granted sales license by Health Canada on first day of legalized marijuana October 17, 2018
Company has begun production of softgel capsules for adult consumer markets
How Genprex took an abandoned pipeline drug and turned it into Oncoprex, an innovative treatment for non-small cell lung cancer October 17, 2018
The biotech was founded by an investment group led by scientists and driven by a no-nonsense CEO whose stake is more than just business as usual
InMed Pharmaceuticals partners with the National Research Council of Canada October 17, 2018
InMed Pharmaceuticals Inc (OTCMKTS:IMLFF) CEO Eric Adams spoke with Christine Corrado at the Bio Investor Forum in San Francisco. InMed Pharmaceuticals specializes in developing novel therapies through research into the pharmacology of cannabinoids coupled with innovative drug delivery systems. InMed's proprietary bioinformatics database drug/disease targeting tool, cannabinoid biosynthesis technology and drug development pipeline are strong […]

STAT Plus: Pharmalittle: Teva faces setback in new migraine drug market; prices for valsartan jump in the U.S. October 17, 2018
Good morning, everyone, and welcome to the middle of the week. Congratulations on making it this far and remember, there are only a few more days until the weekend arrives.…
STAT Plus: Minnesota becomes first state to sue major insulin makers over price-gouging October 16, 2018
In the latest sign of anger over the cost of insulin, the Minnesota attorney general filed a lawsuit accusing the three largest manufacturers with deceptively raising prices, the first state…
STAT Plus: U.S. antitrust regulators are investigating a key supplier of radiology medicines October 16, 2018
A key supplier of radiology medicines in the U.S. is being investigated by antitrust regulators over its business practices.
STAT Plus: Pharmalittle: Legal issues loom over disclosing prices in TV ads; AstraZeneca halts U.K. investment over Brexit worries October 16, 2018
AstraZeneca has suspended investments in the U.K. due to the lack of clarity over the country's looming departure from the European Union.
STAT Plus: A cost-effectiveness watchdog may charge drug makers for ‘early scientific advice’ October 15, 2018
An ICER spokesman said "we would only do so in a manner that would preserve ICER’s independence and integrity."
STAT Plus: Controversy over a Sanofi dengue vaccine caused a crisis of confidence in the Philippines October 15, 2018
After a recent scandal in the Philippines over a Sanofi dengue vaccine, public confidence in vaccines in general has plummeted in the country, according to a new survey.
STAT Plus: Pharmalittle: Trump to require drug prices in ads; Europe cracks down on valsartan ingredients maker October 15, 2018
Europe cracks down on valsartan ingredients maker in China.
STAT Plus: Merck scraps plans to sell a biosimilar version of Lantus as the insulin market gets crowded October 12, 2018
In an unexpected move, Merck (MRK) scrapped plans to market a biosimilar version of the widely used Lantus insulin only a year after winning tentative U.S. regularly approval. The decision…
STAT Plus: Up and down the ladder: The latest comings and goings October 12, 2018
Hired someone new and exciting? Promoting a rising star? Finally solved that hard-to-fill spot?
STAT Plus: Pharmalittle: FDA approves a record number of generics; Bristol-Myers’ Opdivo fails lung cancer study goal October 12, 2018
As of November, specialist clinicians in the U.K. will be able to prescribe cannabis-derived medicinal products for the first time after a change in the law.

MiNA Therapeutics Announces Sosei Will Not Exercise Acquisition Option
MiNA Therapeutics remains on track with current development plans for small activating RNA medicines including clinical development of MTL-CEBPA drug candidate
Oligomerix Awarded $1.98 Million NIH SBIR Phase IIb Grant to Advance its Lead using Transgenic Models for Alzheimer’s Disease and Frontotemporal Dementia
Oligomerix, Inc. announced today the award of a Small Business Innovation Research Phase IIb grant for $1.98 million from the National Institutes of Health, National Institute on Aging.
FDA Approves Pfizer’s Talzenna for Breast Cancer
The U.S. FDA approved Pfizer’s PARP inhibitor, Talzenna (talazoparib), for patients with a germline BRCA-mutated (gBRCAm), HER2-negative breast cancer. The agency also approved Myriad Genetics’ diagnostic assay to identify the mutation.
U.S. District Court in Massachusetts Denies 1Globe's Motion for Preliminary Injunction to Enjoin Sinovac's Issuance of Shares
Sinovac Biotech Ltd. today announced that the United States District Court of the District of Massachusetts denied 1Globe Capital LLC's ("1Globe") August 2018 motion for a preliminary injunction seeking to enjoin Sinovac from issuing shares of Company stock to the PIPE investors or any other individuals pending the outcome of the ongoing litigation between the […]
Sleep Well, Wake up Alert: Eisai and Purdue's Lemborexant Positive in Phase III Trial for Insomnia
Eisai Co. and Purdue Pharma announced topline results from their SUNRISE 2 Phase III clinical trial of lemborexant for sleep-wake disorders.
Biogen and Samsung Bioepis Announce European Launch of IMRALDI™(adalimumab), Solidifying Leadership in European Anti-TNF Market
IMRALDITM (adalimumab), a biosimilar referencing HUMIRA® i, is the third anti-TNF biosimilar developed by Samsung
Acticor Biotech Raises €15.3M In a Series B Financing
New financing will enable the company to launch shortly the first Phase II clinical trial of its lead candidate ACT017 inhibiting GPVI in acute ischemic stroke.
Avidity Biosciences Receives Investment from CureDuchenne
Investment advances pre-clinical development of novel exon skipping therapies for treatment of patients with Duchenne muscular dystrophy
Pear Therapeutics to Participate in BTIG Biotech Conference and Stifel Healthcare Conference
Pear Therapeutics, Inc. today announced its participation in the BTIG Biotech Conference and the Stifel Healthcare Conference.
Medivir Scales Back Research Costs to Focus on Clinical Development
Medivir AB announced today plans to reduce activities not critical to its development pipeline of drug candidates as part of its enhanced focus on clinical stage projects.