Alzheimers and Dementia

Biomarker May Predict Early Alzheimer’s Disease

Researchers at Sanford Burnham Prebys Medical Discovery Institute (SBP) have identified a peptide that could lead to the early detection of Alzheimer’s disease (AD). The discovery, published in Nature Communications, may also provide a means of homing drugs to diseased areas of the brain to treat AD, Parkinson’s disease, as well as glioblastoma, brain injuries […]

Biotechnology Cell Therapy Immunotherapies Uncategorized

Immune cells may heal bleeding brain after strokes

While immune cells called neutrophils are known to act as infantry in the body’s war on germs, a National Institutes of Health-funded study suggests they can act as medics as well. By studying rodents, researchers showed that instead of attacking germs, some neutrophils may help heal the brain after an intracerebral hemorrhage, a form of […]

Alzheimers and Dementia Biotechnology

Demand for Diagnostic for Early Detection of Brain Injury After Surprising Study On NFL Players Brains And CTE

Chronic Traumatic Encephalopathy (CTE) is a slowly developing neurodegenerative condition typical of athletes involved in contact sports. This was evidenced in a recent study in which nearly every former NFL player whose brain was investigated had suffered from CTE.  The findings released this week were part of a study conducted by two leading medical institutions devoted […]

Cell Therapy rare diseases

Rare Type of Immune Cell Responsible for Progression of Heart Inflammation to Heart Failure in Mice

A new study in mice reveals that eosinophils, a type of disease-fighting white blood cell, appear to be at least partly responsible for the progression of heart muscle inflammation to heart failure in mice. In a report on the findings, published in The Journal of Experimental Medicine on March 16, researchers found that while eosinophils […]

Alzheimers and Dementia Biotechnology

Weston Brain Institute Funds Clinical Trials of New Alzheimer’s Treatment

Electrocranial stimulation offers hope for Alzheimer’s patients Funding for clinical trials of a new treatment for Alzheimer’s disease has been announced by the Weston Brain Institute. Dr. Zahra Moussavi, Canada Research Chair in Biomedical Engineering in the Faculty of Engineering, is receiving $1,737,960 for her project on investigating the efficacy of high-frequency rTMS treatment for […]

Alzheimers and Dementia Genomes Neurodegenerative diseases Neurology

Genetic ‘Switch’ Identified As Potential Target For Alzheimer’S Disease

A team at the MRC Clinical Sciences Centre (CSC), based at Imperial College London, has found an important part of the machinery that switches on a gene known to protect against Alzheimer’s Disease. Working in collaboration with scientists at the Hong Kong University (HKU) and the Erasmus University in Rotterdam, CSC associate professor Richard Festenstein […]

Biomarkers

Biomarkers May Help Better Predict Who Will Have a Stroke

People with high levels of four biomarkers in the blood may be more likely to develop a stroke than people with low levels of the biomarkers, according to a study published in the August 24, 2016, online issue of Neurology®, the medical journal of the American Academy of Neurology. “Identifying people who are at risk […]

Gene Therapy Genomes

Experimental Drug Cancels Effect From Key Intellectual Disability Gene in Mice

A University of Wisconsin-Madison researcher who studies the most common genetic intellectual disability has used an experimental drug to reverse — in mice — damage from the mutation that causes the syndrome. The condition, called fragile X, has devastating effects on intellectual abilities. Fragile X affects one boy in 4,000 and one girl in 7,000. […]

Biotechnology Genomes Laboratory Technology

Sophisticated ‘Mini-Brains’ Add to Evidence of Zika’s Toll on Fetal Cortex

Studying a new type of pinhead-size, lab-grown brain made with technology first suggested by three high school students, Johns Hopkins researchers have confirmed a key way in which Zika virus causes microcephaly and other damage in fetal brains: by infecting specialized stem cells that build its outer layer, the cortex. The lab-grown mini-brains, which researchers […]