Biotechnology

New Penn Medicine Center Brings Immunotherapy Research to Brain Tumor Treatment

Today, Penn Medicine is announcing the newest Translational Center of Excellence (TCE) in the Abramson Cancer Center, focused on Glioblastoma Multiforme, the most common and lethal form of brain cancer. The team will investigate new immune therapies for glioblastoma and, in particular, design and test new CAR T cell therapies. This involves engineering patients’ T […]

Biotechnology cancer Cell Therapy Clinical Trials Uncategorized

Penn’s Glowing Cancer Tool Illuminates Benign, but Dangerous, Brain Tumors during Pituitary Surgery

Fluorescent, targeted dye illuminates molecular signature of tumor tissue in personalized surgery. An experimental imaging tool that uses a targeted fluorescent dye successfully lit up the benign brain tumors of patients during removal surgery, allowing surgeons to identify tumor tissue, a new study from researchers at the Perelman School of Medicine at the University of […]

Biotechnology

Immunotherapy for Glioblastoma Well Tolerated; Survival Gains Observed

A phase one study of 11 patients with glioblastoma who received injections of an investigational vaccine therapy and an approved chemotherapy showed the combination to be well tolerated while also resulting in unexpectedly significant survival increases, researchers at the Duke Cancer Institute report. Patients treated with the study drug (dose-intensified temozolomide and vaccines) were continuously […]

cancer Neurology

Medulloblastoma Patients Should Receive Both Chemotherapy And Radiation Post-Surgery

In a recent study, a Yale Cancer Center team revealed that the addition of chemotherapy to postoperative treatment for adults with medulloblastoma improves survival. The benefit of chemotherapy, in addition to craniospinal radiation, was seen in adult patients with medulloblastoma (MB), including those with localized disease who received high-dose radiation treatment following surgery. The findings […]

cancer Cancer Discovery

From Nanotechnology, A Better Prognostic Tool For Brain Cancer

A new nano-fabricated platform for observing brain cancer cells provides a much more detailed look at how the cells migrate and a more accurate post-surgery prognosis for brain cancer (glioblastoma) patients. By creating an environment similar to the one that glioblastoma cells naturally navigate, Yale and Hopkins researchers could accurately predict the clinical outcomes of […]