Neurology Neuroscience

Hypertension Drugs Could Prevent Memory Loss in Lupus Patients, Study Suggests

Researchers from The Feinstein Institute for Medical Research have discovered that the activation of brain cells called microglia likely contributes to the memory loss and other cognitive impairments suffered by many patients with systemic lupus erythematosus (SLE). The study, which will be published September 5 in the Journal of Experimental Medicine, shows that ACE inhibitors—a class […]

Alzheimers and Dementia Biotechnology

Researchers Find a Potential Target for Anti-Alzheimer’s Treatments

Scientists at the Luxembourg Centre for Systems Biomedicine (LCSB) of the University of Luxembourg have identified a gene that may provide a new starting point for developing treatments for Alzheimer’s disease (AD). The USP9 gene has an indirect influence on the so-called tau protein, which is believed to play a significant role in the onset […]

Gene Therapy Genomes

Gene Variant Explains Racial Disparities in Adverse Reactions to Urate-Lowering Drug

A multi-institutional study led by a Massachusetts General Hospital (MGH) investigator finds significant racial disparities in the risk that patients being treated for gout will develop a serious, sometimes life-threatening adverse reaction to the most commonly prescribed medication. The increased risk closely correlates with the frequency of a gene variant previously associated with that adverse […]