Sylvester Comprehensive Cancer Center Researchers Report Positive Results for New Treatment Strategy for Localized Prostate Cancer

A Sylvester Comprehensive Cancer Center research team has found that focal high intensity focused ultrasound (HIFU) is an effective strategy for treating localized prostate cancer while minimizing side effects.

“We conducted the first U.S. study to show the safety and efficacy of focal HIFU in prostate cancer patients,” said Bruno Nahar, M.D., assistant professor of urologic oncology at the Miller School of Medicine. “It offers an alternative treatment for carefully selected patients with localized prostate cancer who are interested in preserving their quality of life.”

Surgery and radiation therapy are the standard treatments for prostate cancer, said Dr. Nahar. However, they can have significant side effects, including incontinence and erectile dysfunction. With focal HIFU therapy, high-energy ultrasound waves deliver heat targets to the cancerous areas, rather than the entire prostate gland. The minimally invasive procedure is done on an outpatient basis, and patients typically go home the same day.

Dr. Nahar said the location, size, and aggressiveness of the tumor are important considerations for focal HIFU treatment. “The tumor needs to be localized to one lobe of the prostate gland, and not be a large-volume cancer,” he said.

Although HIFU received U.S. Food and Drug Administration approval for prostate ablation in November 2015, the University of Miami is one of the first U.S. institutions to offer this procedure, Dr. Nahar said. “Starting in January 2021, we expect this procedure to be fully covered by private insurance, adding to the treatment options we offer. HIFU can bridge the gap between monitoring the cancer and more invasive procedures, such as radiation or surgery.”

Skip to toolbar