cancer Cancer Discovery

Discovery of Pathway Leading to Growth of Colon Cancer Stem Cells Could Lead to New Possibilities in Colorectal Cancer Treatment

In a discovery that may have significant impact on the future of colon cancer treatment and research, scientists at the Helen F. Graham Cancer & Research Institute’s Center for Translational Cancer Research at Christiana Care Health System have defined a key signaling pathway that regulates colon cancer growth. Wilmington, Delaware, Oct. 11, 2018 – In a discovery that may have significant impact on […]

Diabetes

Managing High Blood Pressure in Diabetics May Prevent Life-Threatening Organ Damage

The most effective way to prevent life-threatening complications of extreme hypertension in African-Americans with diabetes is to better control their blood pressure, according to a Rutgers study, the largest of its kind. The study, which appears in Clinical and Experimental Hypertension, included 783 diabetic and 1,001 non-diabetic patients from a New Jersey hospital emergency department that serves […]

cancer Cancer Discovery Cancer screening

New radiotherapy treatment for brain cancer offers superior preservation of cognitive function, Mayo researchers say

 When it comes to radiation therapy to treat brain cancer, hippocampal-avoidance whole-brain radiotherapy in conjunction with the drug memantine better preserved patients’ cognitive function and demonstrated similar cancer control outcomes, compared to traditional whole-brain radiotherapy with memantine. These findings were presented on Tuesday, Oct. 23, by Mayo Clinic researchers at the 2018 annual meetingof the American Society for Radiation Oncology […]

Biotechnology cancer Clinical Trials

Researchers Use New AI Techniques in Clinical Trials for Personalized Cancer Treatment

Researchers are finding new ways to use artificial intelligence and nanotechnology to enhance treatments, from routine dental techniques to attacking cancerous tissue. At the AVS 65th International Symposium and Exhibition, being held Oct. 21-26, 2018, in Long Beach, California, Dean Ho will present the results of two clinical trials that show how AI-enabled personalized medical […]

Biotechnology

New Breakthroughs Offer Hope for Patients with Cystic Fibrosis to Breathe Easier

Two preliminary trials have found that either of two triple-drug regimens could potentially benefit 90 percent of people with cystic fibrosis. The short-term trials found that the drug combinations improved adult patients’ lung function over four weeks. But experts said they were optimistic the results will hold up in the larger, longer-term trials already underway. […]

cancer Cancer Discovery

Compound Derived From Chinese Tree Bark Shows Promise as Treatment for Pancreatic Cancer

 A new derivative of a compound found in the bark of a rare Chinese tree has powerful anticancer properties and a low toxicity profile, according to researchers at Roswell Park Comprehensive Cancer Center. Results of their study of the effects of the compound F118 in pancreatic cancer were published in the Journal of Experimental & Clinical […]

Diabetes

Amount of Weight Regain After Bariatric Surgery Helps Predict Health Risks

Measuring the percentage of weight regained following the maximum amount of weight lost after bariatric surgery can help predict a patient’s risk of several serious health problems, according to a long-term, multicenter study led by University of Pittsburgh Graduate School of Public Health researchers. The results, published today in JAMA, also found that, while on average study participants […]

Breast Cancer cancer Cancer Discovery Cancer screening

Researchers Identify a New Way to Determine Whether Metastatic Cancer Cells in Breast Cancer Patients are Dormant or Soon to Turn Deadly

For the first time ever, Mount Sinai researchers have identified a protein as a marker that can indicate whether a cancer patient will develop a reoccurrence of lethal, metastatic cancer, according to a clinical study published in Breast Cancer Research in October. The researchers found that when cells from a breast cancer patient’s original tumor metastasized into […]

Breast Cancer cancer

Innovative regional anesthesia technique reduces pain, opioid use after mastectomy for breast cancer

Women undergoing mastectomy for breast cancer experience improved postsurgical pain relief and reduced opioid consumption when given a pectoralis nerve plane (PECS) block prior to surgery, suggests research presented at the ANESTHESIOLOGY® 2018 annual meeting. The PECS block is a newer regional anesthesia technique that works by injecting long-acting anesthetics, guided by ultrasound, to numb the front […]

Diagnostic Testing Medical Cannabis

New DNA-based Pathogen Testing Technology for the Cannabis Industry Announced

PathogenDx, Inc., the innovative provider of DNA-based pathogen testing technology for the cannabis industry, announced today the release of the first quantitative microarray-based test for cannabis, PDx-Quant™, which can determine whether or not a sample exceeds a state or a federal regulatory agency’s specific standards.  This one-stop microbial testing technology delivers a completely different level […]

Biotechnology

New approach could jumpstart breathing after spinal cord injury

 A research team at the Krembil Research Institute in Toronto has developed an innovative strategy that could help to restore breathing following traumatic spinal cord injury. The team, led by principal investigator Dr. Michael Fehlings – a neurosurgeon/neuroscientist, specialist in spinal cord injury and senior scientist at UHN – published its findings today in the […]

Parkinson's

Deep Brain Stimulation First Therapy to Slow the Progression of Parkinson’s Disease

Peter Konrad, MD, presents exciting findings that show Deep Brain Stimulation (DBS) of the subthalamic nucleus (STN) in early stage Parkinson’s Disease may slow tremor progress at the Congress of Neurological Surgeon’s (CNS) 2018 Annual Meeting, on Wednesday, October 10, in the General Scientific Session. “DBS is the first therapy to show disease modifying effect—it can […]

Breast Cancer cancer Cancer Discovery

New Study Shows Promise for Targeting Breast Cancer Metastasis

 A new study by University of Kentucky Markey Cancer Center researchers suggests that targeting a protein known as collagen XIII could be key for suppressing breast cancer metastasis. Breast cancers begin in the epithelial cells, which are the cells that line organs and tissues in the body. Generally, most epithelial cells will die after detaching from their […]

cancer Clinical Trials drug development Surgery

Neoadjuvant Combination Checkpoint Blockade Trial Yields High Response Rates for Patients with High-Risk Stage 3 Melanoma

Combination checkpoint blockade before surgery (neoadjuvant therapy) produced a high response rate among patients with high-risk stage 3 melanoma, with nearly half having no sign of disease at surgery, but a high incidence of side effects caused the trial to be closed early. The phase II study was led by researchers at The University of […]

Kidney disease kidney function decline

High Blood Levels of Inflammatory Marker Linked with Kidney Function Decline in Healthy Adults

A large multi-ethnic study of healthy individuals found that high circulating levels of an inflammatory marker are linked with long-term decline of kidney function. The results, which appear in an upcoming issue of the Journal of the American Society of Nephrology (JASN), may lead to new insights on the mechanisms behind the development of kidney […]

Biotechnology

Johns Hopkins Grant Project Looks at Small Cell Lung Cancer Treatment Resistances

 Researchers at the Johns Hopkins Kimmel Cancer Center received a $3.1 million grant to study the resistance of limited stage small cell lung cancer to a combination of chemotherapy and radiotherapy (chemoradiation). The National Institutes of Health awarded the grant to researchers from The Johns Hopkins University, co-led by Luigi Marchionni, M.D., Ph.D., assistant professor of […]