Parkinson's

Deep Brain Stimulation First Therapy to Slow the Progression of Parkinson’s Disease

Peter Konrad, MD, presents exciting findings that show Deep Brain Stimulation (DBS) of the subthalamic nucleus (STN) in early stage Parkinson’s Disease may slow tremor progress at the Congress of Neurological Surgeon’s (CNS) 2018 Annual Meeting, on Wednesday, October 10, in the General Scientific Session. “DBS is the first therapy to show disease modifying effect—it can […]

Neurodegenerative diseases Neurology Neuroscience Parkinson's

Researchers Evaluate Controversial Treatment for Parkinson’s Disease Psychosis

 In the wake of media and public reports about increased mortality linked to a new drug for treating Parkinson’s disease psychosis (PDP) — a symptom of the progressive nervous system disorder in which patients experience hallucinations and delusions — researchers at University of California San Diego School of Medicine conducted a retrospective study of qualifying […]

Parkinson's

ADHD May Increase Risk of Parkinson’s Disease and Similar Disorders

While about 11 percent of children (4-17 years old) nationwide have been diagnosed with attention-deficit hyperactivity disorder (ADHD), the long-term health effects of having ADHD and of common ADHD medications remains understudied. Researchers at University of Utah Health found that ADHD patients had an increased risk of developing Parkinson’s and Parkinson-like diseases than individuals with […]

Neurodegenerative diseases Neurology Neuroscience Parkinson's

Non-Invasive Brain Stimulation May Help Treat Symptoms of Rare Movement Disorders

Electrical stimulation of the brain and spinal cord may help treat the symptoms of rare movement disorders called neurodegenerative ataxias, according to a study published in the August 22, 2018, online issue of Neurology®, the medical journal of the American Academy of Neurology. There are several types of these disorders, which can be hereditary or occur randomly, […]

Neurodegenerative diseases Neurology Parkinson's

A Single Concussion May Increase Risk of Parkinson’s Disease

People who have been diagnosed with a mild concussion, or mild traumatic brain injury, may have a 56 percent increased risk of developing Parkinson’s disease, according to a study published in the April 18, 2018, online issue of Neurology®, the medical journal of the American Academy of Neurology. “Previous research has shown a strong link […]

Parkinson's Pharmaceuticals

Mutation of Worm Gene, Swip-10, Triggers Age-Dependent Death of Dopamine Neurons, Key Feature of Parkinson’s Disease

Dopamine, a signaling chemical in the brain, has the lofty job of controlling emotions, moods, movements as well as sensations of pleasure and pain. Dysfunction of this critical neurotransmitter is the cause of a number of diseases, most notably, Parkinson’s disease. Parkinson’s disease is caused by the death of dopamine-producing cells and most theories of […]

Parkinson's

Faulty Cellular Membrane “Mix” Linked To Parkinson’s Disease

Working with lab-grown human brain cells, Johns Hopkins researchers report they have uncovered a much sought-after connection between one of the most common genetic mutations in Parkinson’s disease and the formation of fatty plaques in the brain thought to contribute to the destruction of motor neurons that characterize the disease. The mutation occurs in a […]

Neuroscience Parkinson's

Parkinson’s drug to Treat OFF Episodes Hits Right Notes in Phase 3 Study

Sunovion Pharmaceuticals Inc. announced top line results from its pivotal Phase 3, randomized, double-blind, placebo-controlled clinical trials from its pivotal Phase 3, randomized, double-blind, placebo-controlled clinical trial, CTH-300, that evaluated apomorphine sublingual film (APL-130277) in patients with Parkinson’s disease (PD) who experience motor fluctuations (OFF episodes). Study CTH-300 met its primary and key secondary endpoints, […]