genomic sequencing Archives – The Bio Connection

First Large-Scale Genomic Analysis of Key Acute Leukemia Will Likely Yield New Therapies

July 3, 2017July 10, 2017 TheBioConnection Comment(0)

A consortium including St. Jude Children’s Research Hospital and the Children’s Oncology Group has performed an unprecedented genomic sequencing analysis of hundreds of patients with T-lineage acute lymphoblastic leukemia (T-ALL). The results provide a detailed genomic landscape that will inform treatment strategies and aid efforts to develop drugs to target newly discovered mutations. The data […]

Human-like walking mechanics evolved before the genus Homo April 23, 2018
A close examination of 3.6-million-year-old hominin footprints discovered in Laetoli, Tanzania, suggests our ancestors evolved the hallmark trait of extended leg, human-like bipedalism substantially earlier than previously thought.
First genetic evidence of ongoing mating between 2 distinct species of guenon monkeys April 23, 2018
A new study of guenon monkeys in Gombe National Park is the first to provide genetic evidence of ongoing mating between two distinct species. These monkeys have successfully been producing hybrid offspring for hundreds maybe even thousands of years. Prior studies have suggested that the different physical characteristics of these monkeys keeps them from interbreeding. […]
Dodo's violent death revealed April 21, 2018
The famous Oxford Dodo died after being shot in the back of the head, according to new research. Using revolutionary forensic scanning technology and world-class expertise, researchers have discovered surprising evidence that the Oxford Dodo was shot in the neck and back of the head with a shotgun.
Bottlenose dolphins recorded for the first time in Canadian Pacific waters April 20, 2018
A large group of common bottlenose dolphins (Tursiops truncatus) have been spotted in Canadian Pacific waters -- the first confirmed occurrence of the species in this area.
Museum researchers rediscover animal not seen in 30 years April 19, 2018
Researchers have rediscovered the San Quintin kangaroo rat (Dipodomys gravipes) in Baja California. The Museum is partnering with Terra and local authorities on a conservation plan for the species, which was last seen in 1986, and was listed as endangered by the Mexican government in 1994. It was held as an example of modern extinction […]
Clear as mud: Desiccation cracks help reveal the shape of water on Mars April 19, 2018
As Curiosity rover marches across Mars, the red planet's watery past comes into clearer focus.
Male contraceptive compound stops sperm without affecting hormones: Study in monkeys April 19, 2018
A new study details how a compound called EP055 binds to sperm proteins to significantly slow the overall mobility of the sperm without affecting hormones, making EP055 a potential 'male pill' without side effects.
A complete cell atlas and lineage tree of the immortal flatworm April 19, 2018
From one stem cell to many differentiated body cells: Scientists have now published a comprehensive lineage tree of a whole adult animal. This was made possible by a combination of RNA and computational technologies.
Unprecedented wave of large-mammal extinctions linked to prehistoric humans April 19, 2018
Homo sapiens, Neanderthals and other recent human relatives may have begun hunting large mammal species down to size -- by way of extinction -- at least 90,000 years earlier than previously thought, according to a new study. The magnitude and scale of the extinction wave surpassed any other recorded during the last 66 million years, […]
Atoms may hum a tune from grand cosmic symphony April 19, 2018
Researchers playing with a cloud of ultracold atoms uncovered behavior that bears a striking resemblance to the universe in microcosm. Their work forges new connections between atomic physics and the sudden expansion of the early universe.

Synergy CHC turns to Instagram influencers to promote its products April 23, 2018
The retailer's roster includes lingerie brand Sneaky Vaunt and FOCUSFactor, a cognitive health supplement
Oragenics raises US$1.8mln to develop treatment for oral mucositis April 23, 2018
Oral mucositis affects about 1 million Americans, says CEO Alan Joslyn
Nephros may use US$2.9mln private placement to uplist to national exchange April 23, 2018
Shares rose after the medical device company announced the cash raise
High Hampton Holdings Corp. sets its sights on Coachella April 23, 2018
The cannabis company may branch out to other states when federal law allows
First Choice Healthcare Solutions expands into new markets after hospital network partnership April 23, 2018
Steward Health Care System invested US$7.5mln with the company in March
Midatech Pharma primed and funded for success April 23, 2018
2018 is shaping up to be a crucial year for the company's drug pipeline
Cannabis cultivator Clinic Nevada selects DigiPath as lab tester April 23, 2018
DigiPath's aims to improve reliability with state of the art lab equipment
Akorn plunges after Germany's Fresenius Kabi ditches US$4.3bn acquisition deal April 23, 2018
Withdrawal follows revelation of "alleged breaches of FDA data integrity requirements" at Akorn
Summit Therapeutics discovers new potential antibiotics for gonorrhoea April 23, 2018
The drug discovery group is working to advance one of the antibiotics candidates to enter studies later this year
ImmuPharma chairman and chief executive upbeat on Lupuzor; industry interest remains strong April 23, 2018
The pair said the debate around the company's flagship drug is far more 'nuanced' than the top-line data might suggest, which explains why potential licensing partners are keen to continue talking to management

STAT Plus: NIH is sued for plans to award exclusive license for CAR-T therapy to Gilead April 20, 2018
A patient advocacy group has filed a lawsuit to block the federal government from awarding an exclusive license to Gilead for an experimental cancer therapy.
STAT Plus: Up and down the ladder: The latest comings and goings April 20, 2018
From new hires to departures and promotions, the latest comings and goings in the pharmaceutical industry.
STAT Plus: Pharmalittle: WHO deals Sanofi a setback over dengue vaccine; who will buy Shire? April 20, 2018
After initially confirming it was in the early stages of considering a possible offer for Shire, Allergan did an about-face and announced it would not bid.
STAT Plus: Glaxo has to face lawsuit by Armenians who couldn’t decipher Avandia warnings April 19, 2018
A lower court will decide whether the plaintiffs, who speak and understand only Armenian, should have been aware of that information.
STAT Plus: Pharmalittle: Shire rejects latest Takeda offer; Greek parliament ends Novartis bribery probe April 19, 2018
The Greek parliament ended a probe into allegations that 10 senior politicians accepted millions of euros in bribes from Novartis.
In the throes of an opioid crisis, prescriptions fell dramatically last year April 19, 2018
The data suggest that the drumbeat of alarm expressed by a plethora of government officials and policymakers is starting to sway medical practice.
STAT Plus: U.S. spending on prescription drugs rose less than 1 percent last year April 19, 2018
Rebates and discounts mean that drug makers are realizing less revenue than the stated list prices for their medicines.
STAT Plus: Which drug makers are most vulnerable to a new cost-shifting maneuver? April 18, 2018
Over the past year, pharmacy benefit managers have deployed a new weapon against the widely used but controversial copay assistance programs that drug makers distribute to consumers. Clumsily called copay…
STAT Plus: Supreme Court weighs whether to review a whistleblower case against Gilead April 18, 2018
A long-running whistleblower suit accused the company of misleading regulators about contaminated ingredients used in various HIV medicines.
STAT Plus: Pharmalittle: Amgen migraine drug show promise; DEA moves to tighten opioid rules April 18, 2018
Colorado is angling to become the latest state to adopt drug pricing transparency legislation.