Diabetes

Managing High Blood Pressure in Diabetics May Prevent Life-Threatening Organ Damage

The most effective way to prevent life-threatening complications of extreme hypertension in African-Americans with diabetes is to better control their blood pressure, according to a Rutgers study, the largest of its kind. The study, which appears in Clinical and Experimental Hypertension, included 783 diabetic and 1,001 non-diabetic patients from a New Jersey hospital emergency department that serves […]

Diabetes

Amount of Weight Regain After Bariatric Surgery Helps Predict Health Risks

Measuring the percentage of weight regained following the maximum amount of weight lost after bariatric surgery can help predict a patient’s risk of several serious health problems, according to a long-term, multicenter study led by University of Pittsburgh Graduate School of Public Health researchers. The results, published today in JAMA, also found that, while on average study participants […]

Biotechnology Cell Therapy Diabetes Pharmaceuticals

Diabetes Drugs Act as Powerful Curb for Immune Cells in Controlling Disease-causing Inflammation

Controlling Immune System Fuel Puts the Brakes on Macrophage Damage When tissue is damaged, one of the body’s first inflammatory immune-system responders are macrophages, cells which are commonly thought of as “construction workers” that clear away damaged tissue debris and initiate repair. However, prolonged inflammation promotes the progression of many diseases, including obesity. Now, a […]

Biotechnology Clinical Trials Diabetes

Experimental Drug Stops Parkinson’s Disease Progression in Mice

Johns Hopkins researchers say they have developed an experimental drug, similar to compounds used to treat diabetes, that slows the progression of Parkinson’s disease itself — as well as its symptoms — in mice. In experiments performed with cultures of human brain cells and live mouse models, they report the drug blocked the degradation of […]

Biotechnology Diabetes Immunotherapies

Untimely Immune Cell Clocks May Contribute To Obesity And Diabetes In Shift Workers

About 15 million Americans don’t have a typical nine-to-five workday, and many of these—nurses, firefighters and flight attendants, among many other professions—may see their schedule change drastically one week to the next. As a result, these shift workers’ biological clocks, which keep track of the time of day, cannot keep accurate time, potentially making the negative […]

Diabetes

Genetic discovery may help better identify children at risk for type 1 diabetes

Six novel chromosomal regions identified by scientists leading a large, prospective study of children at risk for type 1 diabetes will enable the discovery of more genes that cause the disease and more targets for treating or even preventing it. The TEDDY study’s international research team has identified the new gene regions in young people […]

Diabetes

Pain-Free Skin Patch Responds to Sugar Levels for Management of Type 2 Diabetes

Researchers with NIH’s National Institute of Biomedical Imaging and Bioengineering (NIBIB) have devised an innovative biochemical formula of mineralized compounds that interacts in the bloodstream to regulate blood sugar for days at a time. In a proof-of-concept study performed with mice, the researchers showed that the biochemically formulated patch of dissolvable microneedles can respond to […]

Diabetes

Kidney Disease Increases Risk of Diabetes, Study Shows Elevated urea levels likely a culprit

Diabetes is known to increase a person’s risk of kidney disease. Now, a new study from Washington University School of Medicine in St. Louis suggests that the converse also is true: Kidney dysfunction increases the risk of diabetes. Further, the researchers deduced that a likely culprit of the two-way relationship between kidney disease and diabetes […]

Biotechnology Diabetes Pharmaceuticals Prodrug

Targeting a microRNA shows potential to enhance effectiveness of diabetes drugs

Over the past 15 years, University of Alabama at Birmingham endocrinologist Anath Shalev, M.D., has unraveled a crucial biological pathway that malfunctions in diabetes. Her latest discovery in this beta-cell pathway, published in the journal Diabetes, shows the potential to enhance the effectiveness of existing diabetes drugs, as well as reduce some of the unwelcome […]

Diabetes

Towards a safe and scalable cell therapy for type 1 diabetes by simplifying beta cell differentiation

More than 36 million people globally are affected by type 1 diabetes (T1D), a lifelong disorder where insulin producing cells are attacked and destroyed by the immune system resulting in deficient insulin production that requires daily blood glucose monitoring and administration of insulin. While successful outcomes from islet transplantations have been reported, very few patients […]

Biotechnology Diabetes

Higher BMI linked with increased risk of high blood pressure, heart disease, type 2 diabetes

Results of a new study add to the evidence of an association between higher body mass index (BMI) and increased risk of cardiometabolic diseases such as hypertension, coronary heart disease, type 2 diabetes, according to a study published by JAMA Cardiology. A connection between higher BMI and cardiometabolic disease risk usually arise from observational studies […]

Biotechnology Diabetes

Study reveals sweetened drinks during pregnancy puts infants at higher risk for obesity

A recent Danish study of children born to women with gestational diabetes, found that maternal daily consumption of artificially-sweetened beverages during pregnancy was associated with a higher body mass index score and increased risk of overweight/obesity at 7 years. Artificial sweeteners are widely replacing caloric sweeteners, due to the health concern related to sugar-sweetened beverages […]

Diabetes

Improved Options for Diabetics: Insurance Coverage Now Available for Dario’s New Glucose Monitoring Device and App

More than 387 million people are living with diabetes worldwide. This number is expected to grow to 592 million by 2035. Effective daily blood glucose monitoring is a huge factor in the health and wellbeing of diabetics. A new mobile health app and all-in-one blood glucose monitor system from DarioHealth Corp. (DRIO) can improve monitoring […]

cancer Diabetes

Liver Cancer Drug Shows Promise in Preventing Liver Fibrosis and Treating NASH

Namodenoson, a Phase II drug developed by Can-Fite BioPharma Ltd. (NYSE MKT: CANF), has shown in newly published data that it prevents liver (hepatic) fibrosis progression in preclinical studies. “These latest study results add to the growing body of data that demonstrate Namodenoson’s potential efficacy in combating non-alcoholic fatty liver disease (NAFLD), the precursor to […]

Diabetes

Study Suggests New Way to Prevent Vision Loss in Diabetics and Premature Babies

Researchers at Bascom Palmer Eye Institute, part of the University of Miami Miller School of Medicine, have identified a new molecule that induces the formation of abnormal blood vessels in the eyes of diabetic mice. The study, “Secretogranin III as a disease-associated ligand for antiangiogenic therapy of diabetic retinopathy,” which will be published March 22 […]