Biotechnology cancer Cell Therapy

Cell-Penetrating Peptide Delivers Drugs on a Molecular Level

A team of Kennesaw State University faculty and students have developed a novel cell-penetrating peptide technology that could result in new medical treatments ranging from improved cosmetic procedures to helping in the fight against cancer, according to team leader Jonathan McMurry, KSU’s associate vice president for research. McMurry said the researchers’ work, some of which […]

cancer Cancer Discovery

Cell Death – Paradoxically – Promotes Tumor Growth in Most Aggressive Form of Pancreatic Cancer

The most aggressive form of pancreatic cancer – often described as one of the hardest malignancies to diagnose and treat — thrives in the presence of neighboring tumor cells undergoing a particular form of “orchestrated cell death.” This is according to a major study recently published in the journal Nature. The study results revolve around […]

cancer Cancer Discovery Cell Therapy

St. Jude Researchers Reveal How Two Types of Immune Cells Can Arise From One

The fates of immune cells can be decided at the initial division of a cell. Researchers at St. Jude Children’s Research Hospital have discovered that the production of daughter cells with different roles in the immune system is driven by the lopsided distribution of the signaling protein c-Myc. Nudging c-Myc in one direction or the […]

Biotechnology cancer Cancer Discovery

First Computer Program Developed to Detect DNA Mutations in Single Cancer Cells

Researchers at The University of Texas MD Anderson Cancer Center have announced a new method for detecting DNA mutations in a single cancer cell versus current technology that analyzes millions of cells which they believe could have important applications for cancer diagnosis and treatment. The results are published in the April 18 online issue of […]

Biotechnology cancer Cancer Discovery

New technology for detecting malignant melanoma skin cancer

Billions are spent on cancer research, some new treatments are available, but why aren’t we making more progress toward a cure? Because cancer is molecular disease – it’s something going wrong with the “molecular machinery” in the cells of our body that normally produce the millions of molecules that keep us alive and healthy. But […]

cancer

Inhibition of β2-Adrenergic Receptor Reduces Triple-Negative Breast Cancer Brain Metastases: The Potential Benefit of Perioperative β-Blockade.

While we look to invent new medicines to treat cancer, a parallel approach to repurpose existing medicines may be highly effective. Stress, mediated by adrenaline, has been suspected to promote cancer growth and this research study shows that by blocking adrenaline receptors in breast cancers, they are less successful in spreading to and growing in […]

Biotechnology cancer Cancer Discovery

Precision Prevention of Colorectal Cancer

Precision medicine’s public face is that of disease — and better treatments for that disease through targeted therapies. But precision medicine has an unsung partner that could affect the lives of many more people: Precision prevention — a reflection of the growing realization that preventing cancer and other diseases may not be one-size-fits-all. “Precision medicine […]

Biomarkers cancer

New Potential Lung Cancer Biomarkers Identified

A team of West Virginia scientists have made a breakthrough in cancer research that could improve the results patients see from lung cancer treatments. Scientists from the West Virginia University Cancer Institute and the Morgantown-based bio-analytic technology company Protea say they’ve identified changes that occur at the molecular level in lung cancer cells. Those changes […]

cancer Cancer Discovery

People with Hepatitis C Are Two to Five Times More Likely to Develop Certain Head and Neck Cancers

Long associated with liver cancer and non-Hodgkin’s lymphoma, a study from The University of Texas MD Anderson Cancer Center reveals for the first time that the hepatitis C virus (HCV) is associated with certain head and neck cancers. The findings, published in the Journal of the National Cancer Institute, could have significant implications for both […]

Biotechnology cancer Cancer Discovery

Moffitt Cancer Center Researchers Discover Liver Metastases have Different Radiation Sensitivities Based on Primary Tumor Histology

Radiation is a commonly used therapeutic option to treat liver metastases, with the majority of tumors maintained under control after one year. However, some patients do not respond as well to radiation treatment, and the factors that predict patient outcomes are unclear. Moffitt Cancer Center researchers report that liver metastases have different sensitivities to radiation […]

Biotechnology cancer Cancer Discovery Genomes

Spotting Dna Repair Genes Gone Awry

Researchers led by Ludwig Cancer Research scientist Richard Kolodner have developed a new technique for sussing out the genes responsible for helping repair DNA damage that, if left unchecked, can lead to certain cancers. Genome instability suppressing (GIS) genes play an important role in correcting DNA damage involving the improper copying or reshuffling of large […]

Biotechnology cancer Cancer Discovery

University of Pennsylvania to join new collaboration to fight cancer with immunotherapies

The University of Pennsylvania has joined an unprecedented cancer research effort, the Parker Institute for Cancer Immunotherapy, which unites six of the nation’s top medical schools and cancer centers around a shared aim of accelerating breakthrough immunotherapy research that will turn more cancers into a curable disease. The venture is backed by a $250 million […]

Biomarkers cancer Cancer Discovery

New Study Implicates Unusual Class of Circular RNAs in Cancer

Cancer cells are notorious for their genomes gone haywire, often yielding fusion proteins — mash-ups of two disparate genes that, once united, assume new and harmful capabilities. Exactly how such genome scrambling impacts RNA, particularly the vast and mysterious world of non-coding RNA, has been largely unexplored. Now, a team led by investigators at Beth […]

Biotechnology cancer Clinical Trials Radiopharmaceuticals

FDA Greenlights Orphan Drug Status for Radioimmuneconjugate for Treating Refractory and Relapsed Acute Myeloid Leukemia in Elderly Patients

The U.S. Food and Drug Administration (FDA) has granted orphan drug designation for Iomab-B, a radioimmunotherapeutic that conditions relapsed and refractory Acute Myeloid Leukemia (AML) patients for a Hematopoietic Stem Cell Transplant (HSCT), commonly referred to as a Bone Marrow Transplant (BMT). Iomab-B will soon begin a 150 patient, pivotal Phase 3 multicenter trial in […]