Testing for Calcium in the Coronary Arteries Provides Better Way to Predict Heart Attack Events than Stress Testing Alone

Researchers at the Intermountain Medical Center Heart Institute in Salt Lake City have found that incorporating underused, but available, imaging technologies, such as PET/CT scans, more precisely predicts who’s at risk for heart attacks and similar threats — in time to prevent them. Researchers measured the level of calcium in the coronary arteries of patients […]

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Link Found Between Pediatric Osteoporosis and Anti-Inflammatory Drugs

By studying mice in late adolescence, Johns Hopkins University researchers have discovered that the rapid bone growth associated with puberty is slowed not only by fewer cartilage cell divisions but also by the “aging” of bone cell precursor cells. After investigating the signaling molecules that promote this transition, the scientists conclude that some weak and […]

Biotechnology Cell Therapy Immunotherapies Uncategorized

Potential new approach to the treatment of multiple sclerosis

A prospective new method of treating patients with multiple sclerosis has been proposed by researchers of the Mainz University Medical Center working in cooperation with researchers of the University of Montreal. In model trials and experiments employing human endothelial cells, they discovered that the EGFL7 protein hinders the migration of immune cells into the central […]


Multimodal Approach to Pain Management Reduces Opioid Use, Prescriptions After Joint Replacement

A multimodal approach to pain management (using two or more different methods or medications to manage pain) rather than using opioids alone was associated with a decrease in opioid use, opioid prescriptions and common opioid-related complications in patients undergoing total hip or knee replacements, according to a study published today in the Online First edition […]

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IU Research Suggests Failed Osteoarthritis Drug Could Get New Life as Opioid-Addiction Treatment

A new study from Indiana University suggests that a drug proven safe for use in people may prevent opioid tolerance and physical dependence when used in combination with opioid-based pain medications. Researchers in the Linda and Jack Gill Center for Biomolecular Science at IU Bloomington have discovered that a compound previously tested to treat osteoarthritis pain appears […]


Cell Pouch Regenerative Medicine Clinical Trial for Patients with Type 1 Diabetes Supported with Continuous Glucose Monitoring Systems

Patients undergoing an upcoming Phase I/II single site, single arm clinical trial using Sernova’s signature cell pouch technology, will be provided with a glucose monitoring system from Medtronic Minimed, Northridge, CA. Sernova, a clinical stage company developing regenerative medicine technologies for the treatment of chronic diseases including diabetes and hemophilia, announced continuous glucose monitoring systems […]

Biotechnology Heart Health Regenerative Medicine

Resolvin D-1 Limits Kidney Damage After Heart Attacks

A heart attack triggers an acute inflammatory response at the damaged portion of the heart’s left ventricle. If this acute inflammation lingers, it can lead to stretching of the ventricle and heart failure. The inflammation can claim another victim — the kidneys. New research shows that a bioactive compound called resolvin D-1, injected as a […]

Biotechnology Cell Therapy Clinical Trials Infectious Diseases

Research with Zebrafish May Lead to Treatment for Blinding Disorders, Including Glaucoma

Jakub Famulski, an assistant professor of biology in the University of Kentucky College of Arts and Sciences, has received a grant for over $1.8 million from the National Institutes of Health to study the early formation of the anterior segment of the eye. The research has the potential to lead to more treatment options for patients with blinding disorders. […]

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New Stem-Cell Based Stroke Treatment Repairs Damaged Brain Tissue

A team of researchers at the University of Georgia’s Regenerative Bioscience Center and ArunA Biomedical, a UGA startup company, have developed a new treatment for stroke that reduces brain damage and accelerates the brain’s natural healing tendencies in animal models. They published their findings in the journal Translational Stroke Research. The research team led by […]

Biotechnology Cell Therapy Clinical Trials

A Protein Could Make Stem Cell Therapy for Heart Attack Damage More Effective

Researchers may have found a way to reduce ongoing heart damage that occurs long after a severe heart attack by improving the longevity of stem cells injected into the heart. The new study shows that a protein infused into the bloodstream, can improve the healing properties of stem cell therapy in animal models of the […]

Biotechnology cancer Immunotherapies rare diseases

Smart Bomb Virus Shows Promise as Brain Tumor Immunotherapy

A common cold virus engineered to attack the most common and deadly of brain tumors allowed 20 percent of patients with recurrent glioblastoma to live for three years or longer, researchers from The University of Texas MD Anderson Cancer Center report on a phase I clinical trial in the Journal of Clinical Oncology. The altered […]

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IU Advances Fight Against Hepatitis B with ‘Virus-Cracking’ Molecules

Indiana University researchers have made an important step forward in the design of drugs that fight the hepatitis B virus, which can cause liver failure and liver cancer. It’s estimated that 2 billion people worldwide have had a hepatitis B virus infection in their lifetime, with about 250 million — including 2 million Americans — […]

Biotechnology Diabetes Immunotherapies

Untimely Immune Cell Clocks May Contribute To Obesity And Diabetes In Shift Workers

About 15 million Americans don’t have a typical nine-to-five workday, and many of these—nurses, firefighters and flight attendants, among many other professions—may see their schedule change drastically one week to the next. As a result, these shift workers’ biological clocks, which keep track of the time of day, cannot keep accurate time, potentially making the negative […]

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Cascading Inflammation Associated with Lyme Arthritis Linked to Overactive Immune Response

Every year, more than 300,000 Americans contract Lyme disease, an infection caused by Borrelia burgdorferi, a bacterium transferred during a tick bite. In a small percentage of patients, infection symptoms, including arthritis, persist despite antibiotic treatment. Scientists at University of Utah Health believe they identified a mechanism that activates T cells, a key component of […]

Biotechnology Infectious Diseases rare diseases

Study Shows Evidence of Severe and Lingering Symptoms in Some after Treatment for Lyme Disease

In a study of 61 people treated for the bacteria that causes Lyme disease, Johns Hopkins researchers conclude that fatigue, pain, insomnia and depression do indeed persist over long periods of time for some people, despite largely normal physical exams and clinical laboratory testing. “Post-treatment Lyme disease syndrome (PTLDS) is a real disorder that causes […]

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T Cell Therapy Shows Persistent Benefits in Young Leukemia Patients

CHOP Oncologists Update Analysis in Pivotal Global Trial of CAR T-Cell Treatment for Relapsed or Refractory ALL Updated results from a global clinical trial of the CAR T-cell therapy, tisagenlecleucel, a landmark personalized treatment for a high-risk form of acute lymphoblastic leukemia (ALL), reveal that children and young adults continued to show high rates of […]