The Cancer Center of Kansas (CCK) has been added as a new clinical trial site and will be part of an ongoing, multicenter, Phase IIa study of Bria-IMT™ (listed in ClinicalTrials.gov as NCT03066947) in advanced breast cancer, as well as the rollover combination study of BriaCell Therapeutic’s Bria-IMT™ with pembrolizumab or ipilimumab (listed in ClinicalTrials.gov as NCT03328026). Dr. Shaker R. Dakhil, Board certified in Medical Oncology and Internal Medicine, will act as the clinical site’s principal investigator (PI). Under the direction of Dr. Dakhil, the Cancer Center of Kansas lists 16 offices, and 13 Sub Investigators. Dr. Dakhil will work closely with Cancer Insight, LLC., BriaCell’s contract research organization, to manage the clinical and regulatory aspects of the Phase IIa clinical trial in advanced breast cancer on behalf of BriaCell.
With its wide network of facilities and leading oncologists, CCK has been providing the patients in the State of Kansas with leading cancer-related research, diagnosis, and treatment since 1975. The Cancer Center of Kansas team, and its physicians, have received numerous awards for excellent patient care and expertise. The clinical site currently lists 16 offices in the State of Kansas, including their main location in Wichita, and 15 additional participating locations at McPherson, Junction City, Marysville, and Neodesha.
“We are thrilled to be working with a leading oncology team at a well-respected center such as CCK, as we continue the clinical development of Bria-IMT™ in advanced breast cancer,” stated Bill Williams, BriaCell’s President and CEO. “We anticipate that multiple trial locations will provide treatment access to qualified patients in the US Midwest. This new relationship should speed up the pace of recruiting for our Phase II clinical trial of Bria-IMT™ and the rollover study. Our top priority is to obtain data from these studies which will enable us to make Bria-IMT™ immunotherapy available to patients as soon as possible. We believe Bria-IMT™ is a safe and effective treatment. If data from the trial supports its effectiveness, Bria-IMT™ will fill a void in the treatment of advanced breast cancer, currently a huge unmet medical need.”
Dr. Shaker R. Dakhil will serve as the lead Principal Investigator (PI) for Bria-IMT™ and rollover studies. Board certified in Medical Oncology and Internal Medicine since 1981, Dr. Dakhil has served as President of CCK since 2000. He is a clinical Professor of Medicine at the University of Kansas School of Medicine – Wichita and has served as PI for numerous cancer clinical trials.
Dr. Dakhil has lead several earlier cancer research projects and was part of a three-physician team which developed the first implantable central venous catheter (known as port-a-cath), used in cancer care. Dr. Dakhil is a Fellow of the American College of Physicians and holds membership in a number of professional societies in oncology. He has served as President of the Medical Society of Sedgwick County (1997) and is Past President of staff at Via Christi Hospital. Dr. Dakhil founded Wichita Cancer Foundation, a non-profit organization which provides financial assistance for cancer patients. He has been honored with numerous awards including the Healthcare Heroes Lifetime Achievement Award by the Wichita Business Journal in 2014, and has been named each year, from 2005 to 2011, in the Top 1% of Physicians in the Nation by Castle Connolly Medical Ltd. as nationally published by Newsweek, US News and World Report.
“We are grateful to have a top oncology expert such as Dr. Dakhil as the lead PI at CCK in our Phase I/IIa clinical trials of Bria-IMT™,” Dr. Williams said.
“Bria-IMT™ may represent a significant advance in the safe and effective treatment of advanced breast cancer patients,” commented Dr. Dakhil. “Early data from the preliminary trials and ongoing trials have been encouraging, and it is our hope they will be substantiated by these clinical studies at our site. We are excited to be working with the BriaCell team to make these treatments available to advanced breast cancer patients with poor survival prospects”.
The Phase IIa clinical trial of Bria-IMT™ and the Phase I/IIa rollover combination study with Keytruda® and Yervoy® in advanced breast cancer are currently being conducted at five top cancer centers: 1) St. Joseph Health-Sonoma County, Santa Rosa, CA, 2) Everett Clinic and Providence Regional Medical Center, Everett, WA, 3) Jefferson Breast Care Center, Philadelphia, PA, 4) Sylvester Comprehensive Cancer Center, University of Miami in Miami, FL, and 5) Cancer Center of Kansas, Wichita, KS. An earlier site at Florida Cancer Care in Plantation, FL was recently closed.
BriaCell is currently enrolling advanced breast cancer patients in a Phase IIa trial (NCT03066947) with Bria-IMT™ and a rollover trial (NCT03328026) with Bria-IMT™ in combination with other immunotherapies. For further information on the Phase IIa trials, please visit https://clinicaltrials.gov/ct2/show/NCT03066947?term=BriaCell&rank=2.
About The Cancer Center of Kansas
Founded by Dr. Harry Hynes in Wichita, KS, in 1975, Cancer Center of Kansas, provides personalized, quality and innovative cancer care to patients in the mid-west. The center’s mission has been to provide the latest and highest quality diagnostic and therapeutic care to cancer patients through their commitment to excellence in medical oncology and hematology. Since 1987, CCK began extending its coverage throughout the state to serve patients in rural areas such as McPherson, Junction City, Marysville, and Neodesha. Cancer Center of Kansas currently lists 16 participating offices and 14 physicians in the State of Kansas.
With its widespread network of facilities throughout the state of Kansas, top oncologists, and excellent patient care team, CCK is aiming to provide world class cancer care to patients. Their services are focused on multiple aspects of cancer treatment including– diagnosis and treatment, blood and marrow transplants, research and clinical trials, diagnostic imaging, advanced laboratory work, and an oral medications center to better serve their patients.
Throughout the years, the CCK team has received numerous distinctions, awards and recognitions at community, national, and international levels for the the center’s excellence in patient care, and the expertise of its physicians. For the full list of awards, please see: https://cancercenterofkansas.com/awards-recognition/.
For more information on the Cancer Center of Kansas, please visit https://cancercenterofkansas.com/.